Niemann Pick C1 Like 1 Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Plays a major role in cholesterol homeostasis.Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte.Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol.Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia.
Synonyms
NPC1 LIKE 1; NPC1L1.
Gene ID
29881
Swiss Prot
Q9UHC9
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Niemann Pick C1 Like 1
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human NPC1L1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
29881
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