SIRP Alpha Recombinant Antibody, PE Conjugated
Product Specifications
Background
Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function.
Synonyms
CD172a; MFR; MYD 1; p84; PTPNS1; SHPS1; SIRP; SIRPA; SIRPalpha; SIRPalpha1; SIRPalpha2; SIRPalpha3.
Gene ID
140885
Swiss Prot
P78324
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
SIRP Alpha
Clonality
Recombinant
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human SHP substrate 1
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
140885
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