TREX1 Recombinant Antibody, Cy5.5 Conjugated

Product Specifications

Background

Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini.Prevents cell-intrinsic initiation of autoimmunity.Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements.

Synonyms

AGS1; AGS5; CRV; DNase III; DRN3; HERNS; TREX1.

Gene ID

11277

Swiss Prot

Q9NSU2

Host

Rabbit

Cross Reactivity

Human

Target

TREX1

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy5.5

Source

KLH conjugated synthetic peptide derived from human TREX1

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

675nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

11277

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