CD112 Recombinant Antibody, RBITC Conjugated

Product Specifications

Background

Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

Synonyms

HVEB; PRR2; CD112; PVRR2.

Gene ID

5819

Swiss Prot

Q92692

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

CD112

Clonality

Recombinant

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human Nectin 2

Applications

WB, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5819

Available Sizes

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