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METAP2 Recombinant Antibody, PerCP Conjugated

Product Specifications

Background

Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) . The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo.

Synonyms

Amp2; MAP2; Metap2; MNPEP; p67; p67eIF2.

Gene ID

10988

Swiss Prot

P50579

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

METAP2

Clonality

Recombinant

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human METAP2

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10988

Available Sizes

Curated Selection

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