Uric acid-15N2

Uric acid-15N2 is the 15N labeled Uric acid[1]. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[2][3].

Product Specifications

CAS Number

[62948-75-8]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/uric-acid-15n2.html

Purity

99.60

Solubility

H2O : 5.88 mg/mL (ultrasonic; adjust pH to 10 with 1M NaOH)

Smiles

O=C1C2=C([15NH]C([15NH]1)=O)NC(N2)=O

Molecular Formula

C5H4N2 15N2O3

Molecular Weight

170.10

Precautions

H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32 (11) :1839-1845.|[3]Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 202050 (4) :359-375.