MIB1 Recombinant Antibody, PerCP Conjugated

Product Specifications

Background

E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.

Synonyms

Dip1; LVNC7; MIB; mib1; ZZANK2; ZZZ6.

Gene ID

57534

Swiss Prot

Q86YT6

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

MIB1

Clonality

Recombinant

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human MIB1

Applications

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

57534

Available Sizes

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