DARC Recombinant Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines.

Synonyms

CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1.

Gene ID

2532

Swiss Prot

Q16570

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

DARC

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human Atypical chemokine receptor 1

Applications

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

Lot dependent

Dilution

IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2532

Available Sizes

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