DARC Recombinant Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines.
Synonyms
CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1.
Gene ID
2532
Swiss Prot
Q16570
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
DARC
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human Atypical chemokine receptor 1
Applications
IF
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
Lot dependent
Dilution
IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2532
Curated Selection
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