MHI-148

MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells[1].

Product Specifications

CAS Number

[172971-76-5]

Product Name Alternative

IR-808

UNSPSC

12171500

Hazard Statement

H319

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mhi-148.html

Purity

98.39

Solubility

DMSO : 20.83 mg/mL (ultrasonic)

Smiles

CC(C1=CC=CC=C1N/2CCCCCC(O)=O)(C)C2=C/C=C3CCCC(/C=C/C4=[N+](CCCCCC(O)=O)C5=CC=CC=C5C4(C)C)=C\3Cl.[Br-]

Molecular Formula

C42H52BrClN2O4

Molecular Weight

764.23

Precautions

H319

References & Citations

[1]Athira Raveendran, et al. Heptamethine Cyanine Dye MHI-148-Mediated Drug Delivery System to Enhance the Anticancer Efficiency of Paclitaxel. Int J Nanomedicine. 2021 Oct 21;16:7169-7180.