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MMP17 Recombinant Antibody, PE-Cy5.5 Conjugated

Product Specifications

Background

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.

Synonyms

MMP 17; Mmp17; MT MMP4; MT-MMP 4; MT4 MMP; MT4-MMP; MT4MMP; MTMMP4.

Gene ID

4326

Swiss Prot

Q9ULZ9

Cellular Locus

Extracellular, Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

MMP17

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy5.5

Source

KLH conjugated synthetic peptide derived from human MMP17

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4326

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