SMURF2 Recombinant Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent degradation, thereby down-regulating TGF-beta signaling.
Synonyms
HSMURF2; SMUF2_HUMAN; Smurf2.
Gene ID
64750
Swiss Prot
Q9HAU4
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
SMURF2
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human SMURF2
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
64750
Predicted Cross Reactivity
Mouse, Rat
Curated Selection
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