IL-23 Recombinant Antibody, PE Conjugated

Product Specifications

Background

Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity.Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.

Synonyms

IL 23A; IL 23p19; IL12B; IL23; Il23a; IL23P19; P19; SGRF.

Gene ID

51561

Swiss Prot

Q9NPF7

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human

Target

IL-23

Clonality

Recombinant

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human IL 23A

Applications

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

51561

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