Phospho-GCN2 (Thr899) Recombinant Antibody, PE-Cy7 Conjugated

Product Specifications

Background

Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to low amino acid availability.Plays a role as an activator of the integrated stress response (ISR) required for adaptation to amino acid starvation.

Synonyms

GCN2-like protein; GCN2; KIAA1338; EIF2AK4.

Gene ID

440275

Swiss Prot

Q9P2K8

Modification Site

Thr899

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

GCN2

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human GCN2 around the phosphorylation site of T899

Applications

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

440275

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