Phospho-GCN2 (Thr899) Recombinant Antibody, PE Conjugated
Product Specifications
Background
Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to low amino acid availability.Plays a role as an activator of the integrated stress response (ISR) required for adaptation to amino acid starvation.
Synonyms
GCN2-like protein; GCN2; KIAA1338; EIF2AK4.
Gene ID
440275
Swiss Prot
Q9P2K8
Modification Site
Thr899
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
GCN2
Clonality
Recombinant
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human GCN2 around the phosphorylation site of T899
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
440275
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