Phospho-GCN2 (Thr899) Recombinant Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to low amino acid availability.Plays a role as an activator of the integrated stress response (ISR) required for adaptation to amino acid starvation.
Synonyms
GCN2-like protein; GCN2; KIAA1338; EIF2AK4.
Gene ID
440275
Swiss Prot
Q9P2K8
Modification Site
Thr899
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
GCN2
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human GCN2 around the phosphorylation site of T899
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
440275
Curated Selection
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