Phospho-GCN2 (Thr899) Recombinant Antibody

Product Specifications

Background

Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) in response to low amino acid availability.Plays a role as an activator of the integrated stress response (ISR) required for adaptation to amino acid starvation.

Synonyms

GCN2-like protein; GCN2; KIAA1338; EIF2AK4.

Gene ID

440275

Swiss Prot

Q9P2K8

Modification Site

Thr899

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

GCN2

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human GCN2 around the phosphorylation site of T899

Applications

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Phosphorylation

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

440275

Available Sizes

Curated Selection

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