Exportin 1 Recombinant Antibody, Cy5.5 Conjugated

Product Specifications

Background

Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP) . Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.

Synonyms

CRM 1; emb; Exp1; Exportin1; XPO 1.

Gene ID

7514

Swiss Prot

O14980

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

Exportin 1

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy5.5

Source

KLH conjugated synthetic peptide derived from human Exportin 1

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

675nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7514

Predicted Cross Reactivity

Mouse, Rat

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