Exportin 1 Recombinant Antibody, APC Conjugated
Product Specifications
Background
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP) . Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
Synonyms
CRM 1; emb; Exp1; Exportin1; XPO 1.
Gene ID
7514
Swiss Prot
O14980
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Target
Exportin 1
Clonality
Recombinant
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human Exportin 1
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
7514
Predicted Cross Reactivity
Mouse, Rat
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