Presenilin 1 Recombinant Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Requires the presence of the other members of the gamma-secretase complex for protease activity.Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.
Synonyms
AD3; Ad3h; FAD; Protein S182; PS1-CTF12; PSEN1; PSNL1; S182.
Gene ID
5663
Swiss Prot
P49768
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Presenilin 1
Clonality
Recombinant
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human Presenilin 1
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5663
Curated Selection
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