PU.1/Spi1 Recombinant Antibody, APC Conjugated
Product Specifications
Background
Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites. Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions.
Synonyms
Oncogene spi1; PU.1; SFPI1; SPI 1; SPI A; Spi1.
Gene ID
6688
Swiss Prot
P17947
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
PU.1/Spi1
Clonality
Recombinant
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human SPI1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6688
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