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Plexin A1 Recombinant Antibody, PE Conjugated

Product Specifications

Background

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Synonyms

NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1.

Gene ID

5361

Swiss Prot

Q9UIW2

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Target

Plexin A1

Clonality

Recombinant

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human Plexin A1

Applications

WB, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5361

Predicted Cross Reactivity

Human, Mouse

Available Sizes

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