Plexin A1 Recombinant Antibody, APC-Cy7 Conjugated

Product Specifications

Background

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

Synonyms

NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1.

Gene ID

5361

Swiss Prot

Q9UIW2

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Target

Plexin A1

Clonality

Recombinant

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human Plexin A1

Applications

WB, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5361

Predicted Cross Reactivity

Human, Mouse

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