Plexin A1 Recombinant Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
Synonyms
NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1.
Gene ID
5361
Swiss Prot
Q9UIW2
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Target
Plexin A1
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human Plexin A1
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5361
Predicted Cross Reactivity
Human, Mouse
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