LYRIC Recombinant Antibody, PE Conjugated

Product Specifications

Background

Down-regulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

Synonyms

3D3; 3D3/LYRIC; AEG1; Astrocyte elevated gene 1; LYRIC; LYRIC/3D3; Metadherin; MTDH; Protein LYRIC.

Gene ID

92140

Swiss Prot

Q86UE4

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

LYRIC

Clonality

Recombinant

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human MTDH

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

92140

Available Sizes

Curated Selection

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