TRPM7 Recombinant Antibody, RBITC Conjugated

Product Specifications

Background

Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium.Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1) .

Synonyms

ALSPDC; CHAK; CHAK1; LTrpC7; TRPM7.

Gene ID

54822

Swiss Prot

Q96QT4

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

TRPM7

Clonality

Recombinant

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human TRPM7

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

54822

Available Sizes

Curated Selection

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