TRIM25 Recombinant Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.
Synonyms
EFP; RNF147; TRI25; TRIM 25; Trim25; Z147; ZNF147.
Gene ID
7706
Swiss Prot
Q14258
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
TRIM25
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human TRIM25
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
7706
Curated Selection
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