RNF8 Recombinant Antibody, APC-Cy7 Conjugated

Product Specifications

Background

E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.

Synonyms

C3HC4 type zinc finger protein; RNF8.

Gene ID

9025

Swiss Prot

O76064

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Target

RNF8

Clonality

Recombinant

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human RNF8

Applications

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9025

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