RAP80 Recombinant Antibody, PE Conjugated

Product Specifications

Background

Ubiquitin-binding protein.Specifically recognizes and binds 'Lys-63'-linked ubiquitin.Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs) .

Synonyms

BRCA1-A complex subunit RAP80; RAP80; Receptor associated protein 80; RIP110; Rxrip110; UIMC1; X2HRIP110.

Gene ID

51720

Swiss Prot

Q96RL1

Host

Rabbit

Cross Reactivity

Human

Target

RAP80

Clonality

Recombinant

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human RAP80

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

51720

Available Sizes

Curated Selection

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