CRK Recombinant Antibody, Cy5.5 Conjugated

Product Specifications

Background

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Synonyms

CRK; CRKII; p38.

Gene ID

1398

Swiss Prot

P46108

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

CRK

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy5.5

Source

KLH conjugated synthetic peptide derived from human CRK

Applications

WB, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

675nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1398

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