CD209/DC-SIGN Recombinant Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response.
Synonyms
CD209 antigen-like protein A; CDSIGN; CIRE; CLEC4L; DCSIGN; Dendritic cell specific ICAM 3 grabbing nonintegrin 1; HIV GP120 Binding Protein; SIGN-R1; SIGNR5.
Gene ID
30835
Swiss Prot
Q9NNX6
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
CD209/DC-SIGN
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human CD209
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
30835
Curated Selection
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