PDCD4 Recombinant Antibody, Cy7 Conjugated

Product Specifications

Background

Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription.

Synonyms

Death up-regulated gene protein; Dug; H731; Ma3; Neoplastic transformation inhibitor; Nuclear antigen H731; Pdcd4; Programmed cell death protein 4; Tis.

Gene ID

27250

Swiss Prot

Q53EL6

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

PDCD4

Clonality

Recombinant

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human PDCD4

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

27250

Available Sizes

Curated Selection

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