TLR9 Recombinant Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides.Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Synonyms
CD289; TLR9; Toll like receptor 9; Toll like receptor 9 isoform A precursor; Toll like receptor 9 isoform B.
Gene ID
54106
Swiss Prot
Q9NR96
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
TLR9
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human TLR9
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
54106
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