DR5 Recombinant Antibody, Biotin Conjugated
Product Specifications
Background
Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Synonyms
Death receptor 5; TRAIL receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9.
Gene ID
8795
Swiss Prot
O14763
Host
Rabbit
Cross Reactivity
Human
Target
DR5
Clonality
Recombinant
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human DR5
Applications
WB, IP
Purification
Purified by Protein A.
Concentration
Lot dependent
Dilution
WB (1:300-5000), IP (1-2ug)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
8795
Available Sizes
Curated Selection
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