Noxa Recombinant Antibody, Cy5.5 Conjugated
Product Specifications
Background
Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.
Synonyms
APR; ATL-derived; NOXA; Pmaip1; Protein Noxa.
Gene ID
5366
Swiss Prot
Q13794
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
Noxa
Clonality
Recombinant
Isotype
IgG
Conjugation
Cy5.5
Source
KLH conjugated synthetic peptide derived from human PMAIP1
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
675nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5366
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