Noxa Recombinant Antibody, APC Conjugated

Product Specifications

Background

Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.

Synonyms

APR; ATL-derived; NOXA; Pmaip1; Protein Noxa.

Gene ID

5366

Swiss Prot

Q13794

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

Noxa

Clonality

Recombinant

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human PMAIP1

Applications

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5366

Available Sizes

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