VAMP8 Recombinant Antibody, APC-Cy7 Conjugated
Product Specifications
Background
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex.
Synonyms
VAMP8; EDB; Endobrevin; VAMP-8.
Gene ID
8673
Swiss Prot
Q9BV40
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
VAMP8
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human VAMP8
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8673
Predicted Cross Reactivity
Mouse, Rat
Curated Selection
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