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Phospho-CDC42 (Ser71) Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.

Synonyms

CDC42; CDC42Hs; G25K; TKS; MIG5; Ras like protein TC25.

Gene ID

998

Swiss Prot

P60953, P63000

Modification Site

Ser71

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

CDC42

Clonality

Recombinant

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Cdc42 around the phosphorylation site of S71

Applications

WB

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

998

Available Sizes

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