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NOTCH4 Recombinant Antibody, Biotin Conjugated

Product Specifications

Background

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.

Synonyms

NOTC4; hNotch4; INT3; Notch homolog 4.

Gene ID

4855

Swiss Prot

Q99466

Cellular Locus

Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

NOTCH4

Clonality

Recombinant

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Notch 4

Applications

WB

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

4855

Available Sizes

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