UBE2I Recombinant Antibody, PerCP-Cy5.5 Conjugated

Product Specifications

Background

Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity.

Synonyms

C358B7.1; P18; UBC9; UBE2I; SUMO1 protein ligase.

Gene ID

7329

Swiss Prot

P63279

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

UBE2I

Clonality

Recombinant

Isotype

IgG

Conjugation

PerCP-Cy5.5

Source

KLH conjugated synthetic peptide derived from human UBE2I

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

482nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7329

Predicted Cross Reactivity

Rat

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