UBE2I Recombinant Antibody, FITC Conjugated

Product Specifications

Background

Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity.

Synonyms

C358B7.1; P18; UBC9; UBE2I; SUMO1 protein ligase.

Gene ID

7329

Swiss Prot

P63279

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

UBE2I

Clonality

Recombinant

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human UBE2I

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7329

Predicted Cross Reactivity

Rat

Available Sizes

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