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PIM1 Recombinant Antibody, PE-Cy5.5 Conjugated

Product Specifications

Background

Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3) .

Synonyms

Oncogene PIM1; PIM; pim-1 kinase 44 kDa isoform; pim-1 oncogene; pim-1 oncogene (proviral integration site 1) ; PIM1.

Gene ID

5292

Swiss Prot

P11309

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

PIM1

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy5.5

Source

KLH conjugated synthetic peptide derived from human PIM1

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5292

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