Phospho-Histone H2B.1 (Thr129) Recombinant Antibody

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

HTB2; Htb2p; HTB1; Htb1p; Histone H2B.1; Histone H2B.2; SPT12.

Gene ID

851810

Swiss Prot

P02293

Modification Site

Thr129

Host

Rabbit

Cross Reactivity

Human, Yeast

Target

Histone H2B.1

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from yeast Histone H2B.1 around the phosphorylation site of T129

Applications

Purification

Purified by Protein A.

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Phosphorylation

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

851810

Available Sizes

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