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Phospho-Histone H2A (Ser129) Recombinant Antibody, APC-Cy7 Conjugated

Product Specifications

Background

Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Synonyms

FLJ92027; H2A histone family, member C; H2A.1; H2A/c; H2A1; H2AFC; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM.

Gene ID

852283

Swiss Prot

P04912

Modification Site

Ser129

Host

Rabbit

Cross Reactivity

Human, Yeast

Target

Histone H2A

Clonality

Recombinant

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from yeast Histone H2A around the phosphorylation site of S129

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

852283

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