TRAM2 Recombinant Antibody, RBITC Conjugated

Product Specifications

Background

Necessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT) .

Synonyms

KIAA0057; TRAM like protein; Tram2; Translocating chain associating membrane protein 2; Translocation associated membrane protein 2.

Gene ID

9697

Swiss Prot

Q15035

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

TRAM2

Clonality

Recombinant

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human TRAM2

Applications

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9697

Available Sizes

Curated Selection

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