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API2/BIRC3 Recombinant Antibody, APC-Cy7 Conjugated

Product Specifications

Background

Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling.

Synonyms

AIP1; API2; BIRC3; CIAP2; HAIP1; IAP homolog C ; RNF49; MIHC; MALT2; Apoptosis inhibitor 2; IAP2.

Gene ID

330

Swiss Prot

Q13489

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

API2/BIRC3

Clonality

Recombinant

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human BIRC3

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

330

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