PMEL Recombinant Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.

Synonyms

PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV.

Gene ID

6490

Swiss Prot

P40967

Cellular Locus

Extracellular, Secreted

Host

Rabbit

Cross Reactivity

Human

Target

PMEL

Clonality

Recombinant

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human PMEL

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6490

Available Sizes

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