RNF20 Recombinant Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1) . H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively) . It thereby plays a central role inb histone code and gene regulation.
Synonyms
BRE1-A; hBRE1; RING finger protein 20; E3 ubiquitin-protein ligase BRE1A; RNF20.
Gene ID
56254
Swiss Prot
Q5VTR2
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
RNF20
Clonality
Recombinant
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human RNF20
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
56254
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