Cleaved-Caspase 3 p17 Recombinant Antibody, PE Conjugated
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Synonyms
Caspase-3 subunit p17; cleaved Caspase 3; cleaved Caspase-3; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA 1; SCA1; SREBP cleavage activity 1; Yama; CASP3_HUMAN; Caspase-3; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1.
Gene ID
836
Swiss Prot
P42574
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Cleaved-Caspase 3 p17
Clonality
Recombinant
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human caspase-3 p17 subunit
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
Lot dependent
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
836
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6352557-01 0.2 mL
SUMO1 (SUMO1, SMT3C, SMT3H3, UBL1, Small ubiquitin-related modifier 1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1) (Biotin)
Sign In for Pricing
View Details MBS6352557-02 5x 0.2 mL
SUMO1 (SUMO1, SMT3C, SMT3H3, UBL1, Small ubiquitin-related modifier 1, GAP-modifying protein 1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1) (Biotin)
Sign In for Pricing
View Details 
MBS6289055-01 0.2 mL
CRYBB3, CT (CRYBB3, CRYB3, Beta-crystallin B3, Beta-B3 crystallin) (AP)
Sign In for Pricing
View Details 
MBS6289055-02 5x 0.2 mL
CRYBB3, CT (CRYBB3, CRYB3, Beta-crystallin B3, Beta-B3 crystallin) (AP)
Sign In for Pricing
View Details