PSAP Recombinant Rabbit Monoclonal Antibody [JE33-54]

Prosaposin, also known as PSAP, is a protein which in humans is encoded by the PSAP gene. This highly conserved glycoprotein is a precursor for 4 cleavage products: saposins A, B, C, and D. Saposin is an acronym for Sphingolipid Activator PrO[S]teINs. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

A1 activator antibody Cerebroside sulfate activator antibody Co-beta-glucosidase antibody Component C antibody CSAct antibody Dispersin antibody GLBA antibody Glucosylceramidase activator antibody Proactivator polypeptide antibody Proactivator polypeptide precursor antibody Prosaposin (sphingolipid activator protein 1) antibody prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) antibody Prosaposin antibody Protein A antibody Protein C antibody PSAP antibody SAP 1 antibody SAP 2 antibody SAP-1 antibody SAP-2 antibody SAP_HUMAN antibody SAP1 antibody Saposin A antibody Saposin B antibody Saposin B Val antibody Saposin C antibody Saposin D antibody Saposin-D antibody Saposins antibody Sgp1 antibody Sphingolipid activator protein 1 antibody Sphingolipid activator protein 2 antibody Sulfated glycoprotein 1 antibody Sulfatide/GM1 activator antibody

Abbreviation

PSAP, GLBA, SAP1

Swiss Prot

P07602 Human

Cellular Locus

Lysosome; Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within Human PSAP aa 1-150 / 524.

Isotype

IgG

Clone

JE33-54

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

Positive Control

HepG2 cell lysate, U-2 OS cell lysate, U-87 MG cell lysate, A549 cell lysate, SK-Br-3 cell lysate, LNCaP cell lysate, MCF7 cell lysate.

Concentration

1 mg/mL

Dilution

WB: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 58 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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