PSAP Recombinant Rabbit Monoclonal Antibody [JE33-54]
Prosaposin, also known as PSAP, is a protein which in humans is encoded by the PSAP gene. This highly conserved glycoprotein is a precursor for 4 cleavage products: saposins A, B, C, and D. Saposin is an acronym for Sphingolipid Activator PrO[S]teINs. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.
Product Specifications
Product Name Alternative
Abbreviation
PSAP, GLBA, SAP1
Swiss Prot
P07602 Human
Cellular Locus
Lysosome; Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human PSAP aa 1-150 / 524.
Isotype
IgG
Clone
JE33-54
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HepG2 cell lysate, U-2 OS cell lysate, U-87 MG cell lysate, A549 cell lysate, SK-Br-3 cell lysate, LNCaP cell lysate, MCF7 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 58 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
ZNF773 Antibody - N-terminal region: FITC (ARP34878_P050-FITC)